Steroid Congress Scientific Program

Steroid Congress 2023 is Co-Organized by

Dr Trevor M. Penning, Editor In Chief of Steroids

and

Dr Jerzy Adamski, Editor in Chief of the Journal of Steroid Biochemistry and Molecular Biology

In partnership with Elsevier

Bellow is the conference program for Steroid Congress 2023, this schedule may be subject to changes due to unforeseen circumstances and limitations in speaker availability.

You may register for the Congress via the button below.

*Steroid Congress 2023 has limited registration availability, register now to reserve your spot

Friday October 6, 2023

Opening Remarks

Opening Remarks from co-congress organizer and Editor in Chief of Steroid Biochemistry and Molecular Biology, Jerzy Adamski

Intracrinology

Session organized by Sheng-Xian Lin, University Laval, Québec Canada

Steroid derivatives as therapeutic tools for intracrinology – Donald Poirier, CHU de Québec Research Center, Université Laval, Canada
Interaction of steroid enzymes contributing to intracrinology – X. Lin, Université Laval, Canada
11-oxygenated androgens in cancer – Chantal Guilmere, Université Laval, Canada
The estrogen signaling pathway reprograms prostate cancer cell metabolism and supports proliferation and disease progression – Étienne Audet-Walsh, Department of Molecular Medicine, Faculty of Medicine, Université Laval, Canada
Relevance of intra-adipose tissue steroid metabolism in human obesity and associated cardiometabolic alterations – André Tchernof, Canada

Steroid Analytics, Population Steroidomics, New Steroids

Pediatric Steroid Diagnostics – Stefan Wudy, Justus Liebig University, Giessen, Germany
Bringing mass spectrometry-based diagnostic panels into adrenal disorders – Man-Ho Choi, Korea Institute of Science and Technology, Seoul, Korea
Challenges in measuring estrogens and androgens by LC-MS – Clementina Mesaros, University of Pennsylvania, Philadelphia, USA
Longitudinal analysis of blood biomarkers and glucocorticoid dosing from children within the I-CAH Registry – Neil Lawrence, Sheffield University, UK

Poster Presentations

Poster presentations by early stage investigators

Glucocorticoid Receptor as a Therapeutic Target

Long term effects of glucocorticoid therapies and some strategies to reduce them – Onno Meijer, Leiden University Medical Center, Leiden, The Netherlands
Glucocorticoid Receptor Crosstalk as One Way to Alleviate Side Effects – Karolien De Bosscher, Gent University, Gent, Belgium
Insights on anti-inflammatory effects of glucocorticoids and HPA axis regulation in COVID-19 disease – Elena Chetrok Shacham, Emek Medical Center, Afula, Israel
NfKb, interferon regulation – John Cidlowski, NIEHS, USA

Saturday October 7, 2023

Structural Biology of Steroid Receptors

AR dimerization modes: evidence from crystals to animal models – Frank K. Claessens, University of Leuven, Leuven, Belgium
From Steroids to Shape Shifting - how the Androgen Receptor is Primed to Drive Cancer –Elizabeth Wasmuth, University of Texas Health at San Antonio, USA
Domain-domain interactions within nuclear receptors – Fraydoon Rastinejad, University of Oxford, Oxford, UK

Novel Steroid Receptor Ligands

Small Molecule Inhibitors of Androgen Receptor N-Terminus Domain for the Treatment of Splice Variant-Positive Prostate Cancer – Ramesh Narayanan University of Tennessee Health Science Center, Memphis, USA
PROTACS for Nuclear Receptors – Shaomeng Wang, University of Michigan, USA
Photoswitched Remotely Tethered Ligands (PORTL) – Dirk Trauner, University of Pennsylvania, USA
Inhibitors of the transactivation domain of androgen receptor as a therapy for prostate cancer – Marianne D. Sadar, BC Cancer, Vancouver, Canada

Mechanisms of Action of Vitamin D

Molecular mechanisms of vitamin D signalling in the thymus: implications for autoimmunity – John H. White, McGill University, Montreal, Canada
Vitamin D toxicity – Glen Jones, Canada
Vitamin D fortification – Kevin Cashman, Cork, Ireland
Therapeutic Potential of a Novel Vitamin D3 Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding – Andrea Stringer , Australia

New Steroids on the Block-11-Oxygenated Androgens

11-oxyandrogens co-secreting cortisol tumors – Juilee Rege, University of Michigan, Ann Arbor, USA
Regulation of 11-oxyandrogen production – Richard Auchus, University of Michigan, USA
Biosynthesis, metabolism and activity of 11-oxygenated sex steroids – Karl Storbeck, Stellenbosch University, South Africa
11-Oxygenated androgens in health and disease – Adina Turcu, University of Michigan, USA
Classic and 11-oxygenated androgens in serum and saliva across adulthood: a cross-sectional study analyzing the impact of age, body mass index, and diurnal and menstrual cycle variation – Lina Schiffer, Cleveland Clinic Lerner Research Institute, USA

Sunday October 8, 2023

Molecular Phenotyping in Health and Disease

Rare monogenic disorders impacting steroidogenesis – Tülay Guran, Marmara University, Istanbul, Turkey
Monogenic Disorders of Adrenal Steroidogenesis – Elisabeth Baranowski, Birmingham, UK
17-beta-HSD3 Deficiency – Je Qiao, China
HSD17B3 Mutations, genetic penetrance and phenotypes – Alex Odermatt, Switzerland
Sex differences in skeletal and hepatic (patho)physiology: role of sex hormone receptors – Vanessa Dubois. Ghent University, Gent, Belgium

Mechanisms of drug resistance in cancer therapies

Mechanisms of Drug Resistance in Castrate Resistant Prostate Cancer – Nima Sharifi, Cleveland Clinic, USA
Enzalutamide and Abiraterone Drug Resistance – Allen Gao, UC Davis, USA
Androgen receptor splice variants – Stephen Plymate, Fred Hutchinson Cancer Center, Seattle, USA
Spatial transcriptomics and single-cell analyses of estrogen receptor-positive breast cancer – Shiuan Chen, City of Hope, USA

Closing Remarks

Closing remarks from the co-congress organizer and Editor in Chief of Steroids, Trevor M. Penning